Philadelphia positive acute lymphoblastic leukemia 16 years after the apparent cure of acute lymphoblastic leukemia. New leukemia or late relapse?

Haematologica. 1998 Sep;83(9):855-6.

Abstract

A Philadelphia-positive ALL in an adult occurring 21 years after the initial diagnosis is reported here. This case raises the question as to whether or not this event is a relapse or a new leukemia. A possible role of interferon-alpha previously administered to the patient for a chronic viral hepatitis is discussed too.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Antiviral Agents / adverse effects
  • Burkitt Lymphoma / diagnosis*
  • Diagnosis, Differential
  • Fatal Outcome
  • Hepatitis C / drug therapy
  • Hepatitis, Chronic / drug therapy
  • Humans
  • Interferon-alpha / adverse effects
  • Interferon-alpha / therapeutic use
  • Male
  • Neoplasms, Second Primary / diagnosis*
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology
  • Recurrence
  • Time Factors

Substances

  • Antiviral Agents
  • Interferon-alpha