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Treatment of pulmonary tuberculosis in HIV-infected adults: Initiation of therapy

Author
Timothy R Sterling, MD
Section Editor
C Fordham von Reyn, MD
Deputy Editor
Elinor L Baron, MD, DTMH

INTRODUCTION

Initiation of therapy for treatment of drug-susceptible pulmonary tuberculosis (TB) in human immunodeficiency virus (HIV)-infected adults must address potential drug interactions, adverse drug reactions, and optimal timing for initiation of antiretroviral therapy (ART) in ART-naïve patients [1-5].

Issues related to initiation of therapy for treatment of HIV-infected patients with TB are reviewed here. Issues related to follow-up after initiation of therapy are discussed separately. (See "Treatment of pulmonary tuberculosis in HIV-infected adults: Follow-up after initiation of therapy".)

General principles related to antituberculous therapy for treatment of drug-susceptible TB in HIV-uninfected adults are discussed separately. (See "Treatment of drug-susceptible pulmonary tuberculosis in HIV-uninfected adults".)

The clinical features and diagnosis of TB disease in HIV-infected patients are discussed separately. (See "Epidemiology, clinical manifestations, and diagnosis of tuberculosis in HIV-infected patients".)

Beyond issues related to ART discussed here, general principles related to ART are discussed further separately. (See "Selecting antiretroviral regimens for the treatment-naïve HIV-infected patient" and "Overview of antiretroviral agents used to treat HIV".)

                                   
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Literature review current through: Oct 2017. | This topic last updated: Oct 24, 2017.
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