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Treatment of primary aldosteronism

William F Young, Jr, MD, MSc
Norman M Kaplan, MD
Section Editor
André Lacroix, MD
Deputy Editor
Kathryn A Martin, MD


Nonsuppressible (primary) hypersecretion of aldosterone is an uncommon but underdiagnosed cause of hypertension. The classic presenting signs of primary aldosteronism are hypertension and hypokalemia.

Many subtypes of primary aldosteronism have been described since Conn's original report of the aldosterone-producing adenoma in 1954 [1-3]. The most common subtypes are:

Aldosterone-producing adenomas

Bilateral idiopathic hyperaldosteronism

Less common forms include:


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Literature review current through: Jul 2015. | This topic last updated: Mar 6, 2014.
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