Medline ® Abstract for Reference 61
of 'Treatment of male sexual dysfunction'
Tadalafil in the treatment of erectile dysfunction.
Bella AJ, Brock GB
Curr Urol Rep. 2003;4(6):472.
Oral phosphodiesterase-5 inhibitors have emerged as the preferred first-line treatment for erectile dysfunction worldwide because of patient convenience, efficacy, and safety. Clinical trials have shown that tadalafil significantly enhances erectile function across a wide range of etiologies and provides a prolonged period of effectiveness independent of food or alcohol. In this review, the pharmacokinetic and pharmacodynamic characteristics, efficacy, and safety of tadalafil are discussed.
The Department of Surgery, St Joseph's Health Center, The University of Western Ontario, London, Ontario, Canada.