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Treatment of locally recurrent squamous cell carcinoma of the head and neck

Authors
Michael T Milano, MD, PhD
Steven J Chmura, MD, PhD
Daniel J Haraf, MD
Victoria Banuchi, MD, MPH
Dennis Kraus, MD
Section Editors
David M Brizel, MD
Marvin P Fried, MD, FACS
Deputy Editor
Michael E Ross, MD

INTRODUCTION

Recurrent disease is a major cause of morbidity and an obstacle to long-term survival in squamous cell carcinoma of the head and neck. Locoregional recurrences are seen in 15 to 50 percent of patients with squamous cell carcinoma of the head and neck, and this is a major factor contributing to deaths from head and neck cancer [1-3].

Recurrent head and neck cancer is difficult to treat for multiple reasons, including the effects of prior treatment on tumor cells, as well as the infiltrative and multifocal nature that typically characterizes recurrent disease in this area [4].

The approach to treatment for patients with locally recurrent squamous cell carcinoma of the head and neck will be reviewed here. Recurrent nasopharyngeal cancer and recurrent salivary gland tumors are discussed separately.

(See "Treatment of recurrent and metastatic nasopharyngeal carcinoma".)

(See "Malignant salivary gland tumors: Treatment of recurrent and metastatic disease".)

                 

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Literature review current through: Nov 2016. | This topic last updated: Thu Nov 17 00:00:00 GMT+00:00 2016.
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