Treatment of early (stage I and II) head and neck cancer: The larynx
- Wayne M Koch, MD, FACS
Wayne M Koch, MD, FACS
- Professor of Otolaryngology
- Division of Head & Neck Surgery
- The Johns Hopkins Outpatient Center
- Mitchell Machtay, MD
Mitchell Machtay, MD
- Professor and Chair
- Radiation Oncology Department
- Ireland Cancer Center
- University Hospitals Case Medical Center
- Simon Best, MD
Simon Best, MD
- Assistant Professor
- Johns Hopkins Department of Otolaryngology – Head and Neck Surgery
- Section Editors
- Bruce E Brockstein, MD
Bruce E Brockstein, MD
- Section Editor — Cancer of the Head and Neck
- Clinical Professor of Medicine
- University of Chicago Pritzker School of Medicine
- David M Brizel, MD
David M Brizel, MD
- Section Editor — Radiation Therapy
- Leonard R Prosnitz Professor of Radiation Oncology
- Professor of Otolaryngology Head & Neck Surgery
- Duke University Cancer Institute
- Marshall R Posner, MD
Marshall R Posner, MD
- Section Editor — Cancer of the Head and Neck
- Professor of Gene and Cell Medicine
- The Tisch Cancer Institute
- Icahn School of Medicine at Mount Sinai
- Marvin P Fried, MD, FACS
Marvin P Fried, MD, FACS
- Section Editor — Head and Neck Surgery
- Professor and University Chairman, Department of Otorhinolaryngology - Head and Neck Surgery
- Montefiore Medical Center, Albert Einstein College of Medicine
The management of early laryngeal cancer is presented here. The treatment of locoregionally advanced laryngeal cancer is discussed separately, as is the management of metastatic disease.
EPIDEMIOLOGY AND RISK FACTORS
Worldwide, there are an estimated 238,000 cases of laryngeal cancer and 106,000 deaths annually . In the United States, there are approximately 13,400 cases and 3700 deaths due to laryngeal cancer annually .
Laryngeal cancer is diagnosed predominantly in men, which at least in part, reflects in the effects of tobacco and alcohol use. There is also an increased risk in former smokers.
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- EPIDEMIOLOGY AND RISK FACTORS
- STAGING AND ANATOMY
- PRIMARY TREATMENT
- General principles
- - Radiation therapy
- - Surgery
- - Primary tumor
- - Regional lymph nodes
- - Primary tumor
- - Regional lymph nodes
- ADJUVANT THERAPY
- POSTTREATMENT SURVEILLANCE
- INFORMATION FOR PATIENTS
- SUMMARY AND RECOMMENDATIONS