Wilms tumor is the most common renal malignancy in children . Five-year overall survival rates have dramatically improved with multimodal therapy and now approach 90 percent.
The treatment and outcome of Wilms tumor will be reviewed here. The epidemiology, presentation, diagnosis, and staging of Wilms tumor are discussed separately. (See "Presentation, diagnosis, and staging of Wilms tumor".)
Several prognostic factors at the time of initial diagnosis are associated with an increased risk of tumor recurrence or death, and include:
●Tumor histology (anaplasia)