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Medline ® Abstract for Reference 88

of 'The ketogenic diet and other dietary therapies for the treatment of epilepsy'

88
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Efficacy of the Atkins diet as therapy for intractable epilepsy.
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Kossoff EH, Krauss GL, McGrogan JR, Freeman JM
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Neurology. 2003;61(12):1789.
 
The ketogenic diet is effective for treating seizures in children with epilepsy. The Atkins diet can also induce a ketotic state, but has fewer protein and caloric restrictions, and has been used safely by millions of people worldwide for weight reduction. Six patients, aged 7 to 52 years, were started on the Atkins diet for the treatment of intractable focal and multifocal epilepsy. Five patients maintained moderate to large ketosis for periods of 6 weeks to 24 months; three patients had seizure reduction and were able to reduce antiepileptic medications. This provides preliminary evidence that the Atkins diet may have a role as therapy for patients with medically resistant epilepsy.
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Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, MD 21287-1000, USA. ekossoff@jhmi.edu
PMID