Medline ® Abstract for Reference 56
of 'The ketogenic diet and other dietary therapies for the treatment of epilepsy'
56
TI
[Interest of the ketogenic diet in a refractory status epilepticus in adults].
AU
Bodenant M, Moreau C, SejournéC, Auvin S, Delval A, Cuisset JM, Derambure P, Destée A, Defebvre L
SO
Rev Neurol (Paris). 2008;164(2):194.
INTRODUCTION:
Ketogenic diets have been employed for the treatment of intractable epilepsy in children since 1921, although underlying mechanism remains unknown.
OBSERVATION:
We report the case of a 54-year-old man with partial refractory status epilepticus who exhibited a favourable outcome about seven days after introduction of a ketogenic diet in association with antiepileptic drugs.
DISCUSSION:
Although its efficiency was largely demonstrated in children, little is known about the impact of a ketogenic diet in adults with refractory epilepsy.
CONCLUSION:
Introduction of a ketogenic diet requires a multidisciplinary approach. Its usefulness in adult intractable epilepsy and/or refractory status epilepticus merits further study into its efficacy in reducing the frequency of seizures and a possible prolonged effect.
AD
EA 2683, IFR 114, service de neurologie et pathologie du Mouvement, CHRU, 59037 Lille cedex, France.
PMID