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Testicular germ cell neoplasia in situ (formerly called intratubular germ cell neoplasia of unclassified type)

Authors
Ximing J Yang, MD, PhD
Jerome P Richie, MD, FACS
Section Editor
William K Oh, MD
Deputy Editor
Michael E Ross, MD

INTRODUCTION

Testicular germ cell neoplasia in situ (GCNIS; formerly called intratubular germ cell neoplasia of the unclassified type [1]) is generally considered a precursor of all testicular germ cell tumors (GCTs), except for spermatocytic seminomas in older adult men and yolk sac tumors and mature teratomas in infants. However, this is not an epithelial lesion, and thus the latter terms are not preferred. GCNIS is noninvasive because the neoplastic cells are confined within the seminiferous tubules.

GCNIS is discussed here. Related topics include:

(See "Epidemiology of and risk factors for testicular germ cell tumors".)

(See "Clinical manifestations, diagnosis, and staging of testicular germ cell tumors".)

(See "Overview of the treatment of testicular germ cell tumors".)

                      

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Literature review current through: Nov 2016. | This topic last updated: Wed Oct 19 00:00:00 GMT+00:00 2016.
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References
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