Official reprint from UpToDate®
www.uptodate.com ©2017 UpToDate, Inc. and/or its affiliates. All Rights Reserved.

Medline ® Abstract for Reference 37

of 'Tattooing in adolescents and young adults'

Market survey on toxic metals contained in tattoo inks.
Forte G, Petrucci F, Cristaudo A, Bocca B
Sci Total Environ. 2009 Nov;407(23):5997-6002. Epub 2009 Sep 19.
Tattooing practice is adopted worldwide and represents an important socio-cultural phenomenon, but, the injection into the skin of coloring agents as metals might pose a risk for allergies and other skin inflammations as well as for systemic diseases. In this context, 56 inks for tattooing purchased from 4 different supply companies were analyzed for metal concentration. Aliquots of pigments were microwave digested by nitric acid, fluoridric acid and hydrogen-peroxide and Al, Ba, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Sb, Sr and V were quantified by sector field inductively coupled plasma mass spectrometry. Limits of quantification varied from 0.07 ng/ml (Cd) to 10 ng/ml (Al and Fe); recoveries ranged from 92% (Cd and Sb) to 109% (Sr); within- and between-day precisions were 3.2% and 4.67% on average. The relative contribution of metals to the tattoo inks composition was highly variable between brands and colors, even in pigments with the same base color. Elements found as the main components of inks were as follows (in microg/g): Al, 1.59-5893; Ba, 0.058-1226; Cu, 0.076-31,310; Fe, 0.717-88,443; Sr, 0.174-36.4. Toxic metals as Cd, Mn, Pb, Sb and V were over the 1 microg/g in a few cases, while Hg was in traces. Among the allergenic metals, Cr was the highest (0.315-147 microg/g), followed by Ni (0.037-9.59 microg/g) and Co (0.0028-6.43 microg/g) then. On 56 tattoo inks, Cr, Ni and Co exceeded the safe allergological limit of 1 microg/gin 62.5%, 16.1% and 1.8% of cases, respectively.
Istituto Superiore di Sanità, Viale Regina Elena 299, Rome, Italy.