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Systemic treatment for unresectable malignant pleural mesothelioma

Authors
Anne S Tsao, MD
Nicholas Vogelzang, MD
Section Editors
James R Jett, MD
Rogerio C Lilenbaum, MD, FACP
Deputy Editor
Sadhna R Vora, MD

INTRODUCTION

Malignant mesothelioma is a rare neoplasm that arises most commonly from the mesothelial surfaces of the pleural cavity, less commonly from the peritoneal surface, and extremely rarely from the tunica vaginalis or pericardium. It has an extremely poor prognosis; the median survival is 4 to 13 months for untreated patients [1] and 6 to 18 months for treated patients, regardless of the therapeutic approach [2,3].

The systemic treatment of unresectable malignant pleural mesothelioma (MPM) will be reviewed here, while the application of chemotherapy as a component of a combined modality approach that includes definitive surgery is discussed separately. (See "Initial management of malignant pleural mesothelioma".)

Other related topics include:

(See "Presentation, initial evaluation, and prognosis of malignant pleural mesothelioma".)

(See "Pathology of malignant pleural mesothelioma".)

                 

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Literature review current through: Nov 2016. | This topic last updated: Thu Aug 18 00:00:00 GMT 2016.
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