Medline ® Abstract for Reference 44
of 'Surgical treatment of epilepsy in adults'
44
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Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy.
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Jeha LE, Najm IM, Bingaman WE, Khandwala F, Widdess-Walsh P, Morris HH, Dinner DS, Nair D, Foldvary-Schaeffer N, Prayson RA, Comair Y, O'Brien R, Bulacio J, Gupta A, Lüders HO
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Neurology. 2006;66(12):1938.
To assess short- and long-term seizure freedom, the authors reviewed 371 patients who underwent anterior temporal lobectomy to treat pharmacoresistant epilepsy. The mean follow-up duration was 5.5 years (range 1 to 14.1 years). Fifty-three percent of patients were seizure free at 10 years. The authors identified multiple predictors of recurrence. Results of EEG performed 6 months postoperatively correlated with occurrence and severity of seizure recurrence, in addition to breakthrough seizures with discontinuation of antiepileptic drugs.
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Department of Neurology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. jehil@ccf.org
PMID