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Medline ® Abstract for Reference 76

of 'Surgical resection of sporadic pancreatic neuroendocrine tumors'

Laparoscopic distal pancreatectomy offers shorter hospital stays with fewer complications.
DiNorcia J, Schrope BA, Lee MK, Reavey PL, Rosen SJ, Lee JA, Chabot JA, Allendorf JD
J Gastrointest Surg. 2010;14(11):1804. Epub 2010 Jun 30.
BACKGROUND: Laparoscopic distal pancreatectomy (LDP) is increasingly performed for lesions of the body and tail of the pancreas. The aim of this study was to investigate short-term outcomes after LDP compared to open distal pancreatectomy (ODP) at a single, high-volume institution.
METHODS: We reviewed records of patients who underwent distal pancreatectomy (DP) and compared perioperative data between LDP and ODP. Continuous variables were compared using Student's t or Wilcoxon rank-sum tests. Categorical variables were compared using chi-square or Fisher's exact test.
RESULTS: A total of 360 patients underwent DP. Beginning in 2001, 95 were attempted, and 71 were completed laparoscopically with a 25.3% conversion rate. Compared to ODP, LDP had similar rates of splenic preservation, pancreatic fistula, and mortality. LDP had lower blood loss (150 vs. 900 mL, p<0.01), smaller tumor size (2.5 vs. 3.6 cm, p<0.01), and shorter length of resected pancreas (7.7 vs. 10.0 cm, p<0.01). LDP had fewer complications (28.2% vs. 43.8%, p = 0.02) as well as shorter hospital stays (5 vs. 6 days, p<0.01).
CONCLUSIONS: LDP can be performed safely and effectively in patients with benign or low-grade malignant neoplasms of the distal pancreas. When feasible in selected patients, LDP offers fewer complications and shorter hospital stays.
Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, NY, USA.