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Medline ® Abstract for Reference 50

of 'Surgical resection of lesions of the body and tail of the pancreas'

Stump closure of a thick pancreas using stapler closure increases pancreatic fistula after distal pancreatectomy.
Kawai M, Tani M, Okada K, Hirono S, Miyazawa M, Shimizu A, Kitahata Y, Yamaue H
Am J Surg. 2013 Sep;206(3):352-9. Epub 2013 Jun 24.
BACKGROUND: The appropriate surgical stump closure after distal pancreatectomy (DP) is still controversial. This study investigated the benefits and risks of stapler closure during DP.
METHODS: The risk factors of pancreatic fistulas were investigated in 122 DPs among 3 types of stump closure: hand-sewn suture (n = 32), bipolar scissors (n = 45), and stapler closure (n = 45).
RESULTS: There was no significant difference in the incidence of pancreatic fistula between the 3 types of stump closure (hand-sewn suture [44%]vs bipolar scissors [37.7%]vs stapler closure [35.5%]). By using receiver operating characteristics curves, 12 mm was the best cutoff value of the thickness of the pancreas for pancreatic fistulas after DP using stapler closure. Three factors (ie, male sex, body mass index>25 kg/m(2), and stapler closure) were independent risk factors of pancreatic fistulas after DP with a pancreas thicker than 12 mm.
CONCLUSIONS: A pancreas thicker than 12 mm significantly increased the incidence of pancreatic fistulas after DP using stapler closure.
Second Department of Surgery, Wakayama Medical University, School of Medicine, Japan.