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Medline ® Abstract for Reference 46

of 'Surgical resection of lesions of the body and tail of the pancreas'

Stapler vs suture closure of pancreatic remnant after distal pancreatectomy: a meta-analysis.
Zhou W, Lv R, Wang X, Mou Y, Cai X, Herr I
Am J Surg. 2010 Oct;200(4):529-36. Epub 2010 Jun 9.
BACKGROUND: Suture closure and stapler closure of the pancreatic remnant after distal pancreatectomy are the techniques used most often. The ideal choice remains a matter of debate.
METHODS: Five bibliographic databases covering 1970 to July 2009 were searched.
RESULTS: Sixteen articles met the inclusion criteria. Stapler closure was performed in 671 patients, while suture closure was conducted in 1,615 patients. The pancreatic fistula rate ranged from 0% to 40.0% for stapler closure of the pancreatic stump and from 9.3% to 45.7% for the suture closure technique. There were no significant difference between the stapler and suture closure groups with respect to the pancreatic fistula formation rate (22.1% vs 31.2%; odds ratio, .85; 95% confidence interval, .66-1.08), although there was a trend toward favoring stapler closure. In 4 studies including 437 patients, stapler closure was associated with a trend (not statistically significant) toward a reduction in intra-abdominal abscess (odds ratio, .53; 95% confidence interval, .24-1.15).
CONCLUSIONS: No significant differences occur between suture and stapler closure with respect to the pancreatic fistula or intra-abdominal abscess after distal pancreatectomy, though there is a trend favoring stapler closure.
Department of General Surgery, Affiliated Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.