Case report: failure of subcutaneous ivermectin in treating Strongyloides hyperinfection

Am J Trop Med Hyg. 2008 Dec;79(6):853-5.

Abstract

A man with Escherichia coli meningitis and bacteremia, while on dexamethasone, developed Strongyloides hyperinfection syndrome and died despite salvage therapy with subcutaneous ivermectin. We report the first documented total and free levels of subcutaneous ivermectin used for therapy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Antiparasitic Agents / administration & dosage
  • Antiparasitic Agents / therapeutic use
  • Humans
  • Injections, Subcutaneous
  • Ivermectin / administration & dosage*
  • Ivermectin / therapeutic use*
  • Male
  • Strongyloides stercoralis*
  • Strongyloidiasis / complications
  • Strongyloidiasis / drug therapy*
  • Strongyloidiasis / parasitology

Substances

  • Antiparasitic Agents
  • Ivermectin