Abstract
Strongyloides stercoralis is an intestinal nematode that causes human infections and whose life cycle has special features, including autoinfection. Strongyloides infection may be asymptomatic for years, owing to a low parasite load. During immunosuppressive therapy, however, if cellular immunity is depressed, autoinfection can occur at a higher rate, resulting in hyperinfection syndrome. In this specific circumstance, it can become a fatal illness. We describe a case of hyperinfection syndrome in a liver transplant recipient and also review the literature.
MeSH terms
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Adult
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Animals
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Anthelmintics / therapeutic use
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Fatal Outcome
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Graft Rejection / prevention & control
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Humans
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Immunosuppressive Agents / adverse effects*
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Immunosuppressive Agents / therapeutic use
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Liver Transplantation / adverse effects*
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Male
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Postoperative Complications / diagnosis
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Postoperative Complications / drug therapy
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Postoperative Complications / parasitology*
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Recurrence
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Strongyloides stercoralis*
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Strongyloidiasis / diagnosis
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Strongyloidiasis / drug therapy
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Strongyloidiasis / etiology*
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Superinfection / diagnosis
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Superinfection / drug therapy
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Superinfection / etiology*
Substances
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Anthelmintics
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Immunosuppressive Agents