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Stomatocytosis and xerocytosis

Carlo Brugnara, MD
Section Editor
Donald H Mahoney, Jr, MD
Deputy Editor
Jennifer S Tirnauer, MD


Hereditary stomatocytosis (HSt) and hereditary xerocytosis (HX) are rare disorders that present with various degrees of hemolytic anemia and abnormal red blood cell (RBC) morphologies. Both types of disorders are characterized by alterations in RBC hydration. Occasionally, stomatocytes or xerocytes are seen in other inherited or acquired conditions.

This topic discusses the mechanisms, evaluation, and management of stomatocytosis and xerocytosis.

Our approaches to the patient with hemolytic anemia and other RBC morphologic abnormalities are discussed separately:

Anemia (child) – (See "Approach to the child with anemia".)

Anemia (adult) – (See "Approach to the adult patient with anemia".)

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Literature review current through: Nov 2017. | This topic last updated: Aug 18, 2017.
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