Medline ® Abstract for Reference 57
of 'Stevens-Johnson syndrome and toxic epidermal necrolysis: Pathogenesis, clinical manifestations, and diagnosis'
57
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Stevens-Johnson syndrome limited to multiple sites of radiation therapy in a patient receiving phenobarbital.
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Duncan KO, Tigelaar RE, Bolognia JL
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J Am Acad Dermatol. 1999;40(3):493.
Stevens-Johnson syndrome (SJS) is a severe cutaneous eruption that most often appears as an adverse reaction to a medication. There have been 21 reported cases of atypical erythema multiforme, toxic epidermal necrolysis, and SJS arising in patients receiving radiation therapy in addition to phenytoin, phenobarbital, or carbamazepine. We report the second case of SJS resulting from concomitant phenobarbital and radiation therapy, in which the eruption was limited to the sites of radiation, which were multiple.
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Department of Dermatology, Yale University School of Medicine, New Haven, CT 06520-8059, USA.
PMID