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Spontaneous intracerebral hemorrhage: Pathogenesis, clinical features, and diagnosis

INTRODUCTION

Intracerebral hemorrhage (ICH) is the second most common cause of stroke, trailing only ischemic stroke in frequency [1,2]. Estimates of the annual incidence range from 16 to 33 cases per 100,000 [3]. There are many underlying pathological conditions associated with ICH; hypertension, amyloid angiopathy, ruptured saccular aneurysm, and vascular malformation account for the majority of cases.

The pathogenesis, epidemiology, clinical features, and diagnosis of ICH will be reviewed here, with an emphasis upon hypertensive hemorrhage. The prognosis and treatment of ICH are discussed separately. (See "Spontaneous intracerebral hemorrhage: Treatment and prognosis".)

PATHOGENESIS

Etiologies — Causes of nontraumatic ICH include [4-6]:

Hypertension

Cerebral amyloid angiopathy

                      

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Literature review current through: Oct 2014. | This topic last updated: Dec 4, 2013.
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