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Medline ® Abstract for Reference 7

of 'Sleep disorders in hospitalized adults: Evaluation and management'

Risk of sleep apnea in hospitalized older patients.
Shear TC, Balachandran JS, Mokhlesi B, Spampinato LM, Knutson KL, Meltzer DO, Arora VM
J Clin Sleep Med. 2014;10(10):1061. Epub 2014 Oct 15.
BACKGROUND/OBJECTIVES: To assess the prevalence of undiagnosed obstructive sleep apnea (OSA) among general medical inpatients and to investigate whether OSA risk is associated with in-hospital sleep quantity and quality.
DESIGN: Prospective cohort study.
SETTING: General medicine ward in academic medical center.
PARTICIPANTS: 424 hospitalized adult patients≥50 years old without a sleep disorder diagnosis (mean age 65 years, 57% female, 72% African American).
MAIN MEASURES: The Berlin questionnaire, a validated screen for determining risk of OSA, was administered to hospitalized medical patients. Sleep duration and efficiency were measured via wrist actigraphy. Self-reported sleep quality was evaluated using Karolinska Sleep Quality Index (KSQI).
KEY RESULTS: Two of every 5 inpatients≥50 years old (39.5%, n = 168) were found to be at high risk for OSA. Mean in-hospital sleep duration was∼5 h and mean sleep efficiency was 70%. Using random effects linear regression models, we found that patients who screened at high risk for OSA obtained∼40 min less sleep per night (-39.6 min [-66.5, -12.8], p = 0.004). These findings remained significant after controlling for African American race, sex, and age quartiles. In similar models, those patients who screened at high risk had∼5.5% less sleep efficiency per night (-5.50 [-9.96, -1.05], p = 0.015). In multivariate analysis, patients at high risk for OSA also had lower self-reported sleep quality on KSQI (-0.101 [-0.164, -0.037], p = 0.002).
CONCLUSION: Two of every 5 inpatients older than 50 years screened at high risk for OSA. Those screening at high risk have worse in-hospital sleep quantity and quality.
COMMENTARY: A commentary on this article appears in this issue on page 1067.
Pritzker School of Medicine, University of Chicago, Chicago, IL.