Single umbilical artery
- Martin L Gimovsky, MD
Martin L Gimovsky, MD
- Clinical Professor
- Department of Obstetrics, Gynecology and Reproductive Science
- Mount Sinai School of Medicine
- Eva Tejero Rosa, MS, CGC
Eva Tejero Rosa, MS, CGC
- Supervisor/Lead Genetic Counselor
- Atlantic Health System
- Waldo Sepulveda, MD
Waldo Sepulveda, MD
- Director, FETALMED
- Maternal-Fetal Diagnostic Center, Santiago, Chile
- Section Editors
- Deborah Levine, MD
Deborah Levine, MD
- Section Editor — Imaging
- Professor of Radiology
- Director of Ob/Gyn Ultrasound
- Department of Radiology
- Beth Israel Deaconess Medical Center
- Louise Wilkins-Haug, MD, PhD
Louise Wilkins-Haug, MD, PhD
- Section Editor — Prenatal Diagnosis and Genetics
- Professor of Obstetrics, Gynecology, and Reproductive Biology
- Harvard Medical School
The umbilical cord typically contains two arteries and one vein. Single umbilical artery (SUA) refers to a variation of umbilical cord anatomy in which there is only one umbilical artery. It may be an isolated finding, or associated with aneuploidy or other congenital anomalies.
Three mechanisms have been proposed to explain the development of SUA :
●Secondary atresia or atrophy of a previously normal umbilical artery
●Primary agenesis of one of the umbilical arteries
●Persistence of the original single allantoic artery of the body stalkTo continue reading this article, you must log in with your personal, hospital, or group practice subscription. For more information on subscription options, click below on the option that best describes you:
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- PREVALENCE AND EPIDEMIOLOGY
- RISK FACTORS
- CLINICAL PRESENTATION
- Normal three-vessel cord
- Single umbilical artery
- Differential diagnosis
- - Fused arteries at the insertion site
- - Hypoplasia of one umbilical artery
- POSTDIAGNOSTIC EVALUATION
- Assessment for associated abnormalities
- Fetal genetic studies
- PREGNANCY MANAGEMENT
- Monitoring for growth restriction
- Antepartum fetal monitoring
- Special issues
- - Cordocentesis
- - First-trimester diagnosis
- PREGNANCY OUTCOME
- Preterm delivery
- Small for gestational age and birth weight
- Perinatal outcome
- Long-term outcome in offspring
- SUMMARY AND RECOMMENDATIONS