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Serum cardiac biomarkers in patients with renal failure

Authors
Christopher deFilippi, MD, FACC
William L Henrich, MD, MACP
Section Editors
Jeffrey S Berns, MD
Allan S Jaffe, MD
Deputy Editor
Alice M Sheridan, MD

INTRODUCTION

Cardiac biomarkers are used in conjunction with symptoms, electrocardiographic (ECG) changes, and cardiac imaging to diagnosis acute myocardial infarction (AMI) in patients with chronic kidney disease (CKD) [1]. Cardiac biomarkers are also used to predict short- and long-term adverse outcomes.

The principal cardiac biomarkers are cardiac troponin T (cTnT), cardiac troponin I (cTnI), and the MB isoenzyme of creatine kinase (CK-MB). (See "Troponin testing: Clinical use".)

This topic reviews the clinical use of cardiac troponins and CK-MB in patients with CKD. The use of these biomarkers in patients with normal renal function is discussed separately. (See "Troponin testing: Clinical use".)

The use of other enzymes in patients with CKD is discussed separately. (See "Serum enzymes in patients with renal failure".)

The risk of coronary artery disease (CAD) among dialysis and nondialysis patients with CKD is discussed separately. (See "Chronic kidney disease and coronary heart disease" and "Clinical manifestations and diagnosis of coronary heart disease in end-stage renal disease (dialysis)".)

      

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Literature review current through: Nov 2016. | This topic last updated: Wed Jun 01 00:00:00 GMT+00:00 2016.
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