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Medline ® Abstract for Reference 63

of 'Red blood cell transfusion in adults: Storage, specialized modifications, and infusion parameters'

63
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Elimination of blood group antigens: hope and reality.
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Bagnis C, Chiaroni J, Bailly P
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Br J Haematol. 2011;152(4):392. Epub 2011 Jan 7.
 
In transfusion medicine, three major issues, i.e. heterogeneity of human blood groups, dependence of blood supply on donation, and shortage of some phenotypes, oblige clinicians to juggle with available biological material to avoid or limit post-transfusion reactions. This 'fact of life' has given impetus to a 30-year-old quest to achieve interchangeability of blood products between donors and recipients by eliminating blood group antigens.
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Laboratoire Hématologie Moléculaire,Établissement Français du Sang Alpes Méditerranée, UMR 6578, Universitéde la Méditerranée, Marseille, France.
PMID