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Related articles

Recognition of monoclonal proteins

INTRODUCTION

The monoclonal gammopathies (paraproteinemias or dysproteinemias) are a group of disorders characterized by the proliferation of a single clone of plasma cells, which produces an immunologically homogeneous protein commonly referred to as a paraprotein or monoclonal protein (M-protein, where the "M" stands for monoclonal). (See 'Definition of an M-protein' below.)

A complete immunoglobulin consists of two heavy polypeptide chains of the same class designated by a capital letter and a corresponding Greek letter:

Gamma in IgG

Alpha in IgA

Mu in IgM

                            

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Literature review current through: Jun 2014. | This topic last updated: Aug 21, 2013.
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