Medline ® Abstract for Reference 62
of 'Reactive airways dysfunction syndrome and irritant-induced asthma'
Can reactive airways dysfunction syndrome (RADS) transform into occupational asthma due to "sensitisation" to isocyanates?
Leroyer C, Perfetti L, Cartier A, Malo JL
The case history is described of a worker who presented with a history suggestive of reactive airways dysfunction syndrome which occurred after an acute high level inhalation of diphenylmethane diisocyanate. Further exposure at work, at a time when concentrations of isocyanates were no longer "irritant", suggested occupational asthma; this diagnosis was confirmed by a specific inhalation challenge test.
DEpartment of Chest Medicine, Hôpital du Sacré-Coeur, Gouin, Montréal Canada.