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Medline ® Abstract for Reference 51

of 'Reactive airways dysfunction syndrome and irritant-induced asthma'

Long-term respiratory symptoms in World Trade Center responders.
Mauer MP, Cummings KR, Hoen R
Occup Med (Lond). 2010;60(2):145.
BACKGROUND: New York State (NYS) employees who responded to the World Trade Center (WTC) disaster on or after 11 September 2001 potentially experienced exposures that might have caused persistent respiratory effects. NYS responders represent a more moderately exposed population than typical first responders.
AIMS: To assess whether NYS employees who were WTC responders were more likely than controls to report lower respiratory symptoms (LRS) or a diagnosis of asthma 5 years post-9/11. Persistence and severity of symptoms were also evaluated.
METHODS: Participants were initially mailed self-administered questionnaires (initial, Year 1, Year 2) and then completed a telephone interview in Year 3. Data were analysed using Poisson's regression models.
RESULTS: WTC exposure was associated with LRS, including cough symptoms suggestive of chronic bronchitis, 5 years post-9/11. When exposure was characterized using an exposure assessment method, the magnitude of effect was greater in those withexposure scores above the mean. WTC exposure was associated with persistence of LRS over the 3 year study period. Results also suggest that participants with the highest exposures were more likely to experience increased severity of their asthma condition and/or LRS.
CONCLUSIONS: Our findings suggest that even in a moderately exposed responder population, lower respiratory effects were a persistent problem 5 years post-9/11, indicating that some WTC responders require ongoing monitoring.
Bureau of Occupational Health, Center for Environmental Health, New York State Department of Health, Troy, NY 12180, USA. mpm08@health.state.ny.us