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Psittacosis

Author
Michael J Richards, MD, FRACP
Section Editor
John G Bartlett, MD
Deputy Editor
Anna R Thorner, MD

INTRODUCTION

Psittacosis, also known as ornithosis, is usually a disease with prominent systemic manifestations and some respiratory symptoms. This infection, caused by Chlamydia psittaci, is transmitted to humans predominantly from birds.

The epidemiology, clinical features, diagnosis, and treatment of psittacosis will be discussed here. Pneumonia caused by Chlamydia spp is discussed separately. (See "Pneumonia caused by Chlamydia pneumoniae in adults" and "Pneumonia caused by Chlamydia species in children".)

MICROBIOLOGY

C. psittaci is an obligate intracellular bacterium. There are 10 known genotypes based on sequencing of the major outer protein gene, ompA [1]. Each genotype has host preferences and virulence characteristics, although these overlap. Knowledge of the pathogenesis at a cellular and molecular level is growing [2].

EPIDEMIOLOGY

Psittacosis has been recognized throughout the world, including the United States, the United Kingdom, Europe, the Middle East, and Australia. Birds are the primary reservoir, but transmission from other animals has also been reported. The disease usually occurs sporadically, but outbreaks caused by contact with an infected bird are not uncommon [3]. Outbreaks related to pet shops, aviaries, a veterinary hospital, poultry flocks [4], and turkey and duck processing have been described [5-9].

Birds — Most patients with psittacosis have a history of contact with birds. C. psittaci has been documented in at least 460 species from 30 bird orders, including turkeys, pheasants, chickens, and even ostriches and penguins [10]. Migratory birds, including geese, may carry this pathogen [11]. Most humans are infected from birds of the order psittaciformes, which includes budgerigars, cockatiels, cockatoos, and parrots. In France, mule ducks are associated with human disease through heavy shedding, although the ducks are asymptomatic [12]. Each bird order tends to be infected by a predominant genotype of C. psittaci.

                                   

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Literature review current through: Nov 2016. | This topic last updated: Thu Jul 16 00:00:00 GMT+00:00 2015.
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