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Pseudomonas aeruginosa skin, soft tissue, and bone infections

Souha S Kanj, MD
Daniel J Sexton, MD
Section Editor
Stephen B Calderwood, MD
Deputy Editor
Allyson Bloom, MD


Pseudomonas aeruginosa is one of the most commonly considered gram-negative aerobic bacilli in the differential diagnosis of gram-negative infections. Consideration of this organism is important because it causes severe hospital-acquired infections, especially in immunocompromised hosts, is often antibiotic resistant, complicating the choice of therapy, and is associated with a high mortality rate.

The clinical manifestations, diagnosis, and treatment of P. aeruginosa skin, soft tissue, and bone infections will be reviewed here.

The general principles of antimicrobial treatment of infections caused by P. aeruginosa, including antibiotic options and decisions on combination therapy, are discussed in detail elsewhere. (See "Principles of antimicrobial therapy of Pseudomonas aeruginosa infections".)

The clinical manifestations and management of other P. aeruginosa infections and the epidemiology and pathogenesis of infection with this organism are also discussed separately.

(See "Epidemiology, microbiology, and pathogenesis of Pseudomonas aeruginosa infection".)


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Literature review current through: Sep 2016. | This topic last updated: Dec 17, 2015.
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