Pseudomonas aeruginosa pneumonia
- Souha S Kanj, MD
Souha S Kanj, MD
- Professor of Medicine
- Head, Division of Infectious Diseases,
- Chairperson, Infection Control Program
- American University of Beirut Medical Center
- Daniel J Sexton, MD
Daniel J Sexton, MD
- Editor-in-Chief — Infectious Diseases
- Section Editor — Bacterial Infections
- Professor of Medicine
- Duke University Medical Center
Pseudomonas aeruginosa is one of the most important and most commonly considered pathogens in the differential diagnosis of gram-negative infections. Consideration of this organism is important because it causes severe hospital-acquired infections, especially in immunocompromised hosts, is often antibiotic resistant, complicating the choice of therapy, and is associated with a high mortality rate.
The clinical manifestations, diagnosis, and treatment of P. aeruginosa pneumonia will be reviewed here.
The general principles of antimicrobial treatment of infections caused by P. aeruginosa, including antibiotic options and decisions on combination therapy, are discussed in detail elsewhere. (See "Principles of antimicrobial therapy of Pseudomonas aeruginosa infections".)
The clinical manifestations and management of other P. aeruginosa infections and the epidemiology and pathogenesis of infection with this organism are also discussed separately.
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- Hospital-acquired pneumonia
- Community-acquired pneumonia
- Equipment-related outbreaks
- CLINICAL FEATURES
- Signs and symptoms
- Empiric antimicrobial therapy
- Directed antimicrobial therapy
- - Regimen choice
- - Duration of therapy
- Inhaled antibiotics
- Strategies for drug resistant isolates
- OUTCOME AND PROGNOSIS
- PSEUDOMONAS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
- SUMMARY AND RECOMMENDATIONS