Prurigo nodularis (PN) is a chronic skin disorder characterized by multiple, firm, pruritic nodules typically localized to the extensor surface of the extremities (picture 1A-B). PN is frequently associated with a history of atopic dermatitis or chronic pruritus [1,2].
Prurigo nodularis will be discussed in this topic. Other skin conditions associated with chronic pruritus, including atopic dermatitis, nodular scabies, lichen planus, and bullous pemphigoid, are discussed separately.
●(See "Pruritus: Etiology and patient evaluation" and "Pruritus: Overview of management".)
●(See "Epidemiology, clinical manifestations, and diagnosis of atopic dermatitis (eczema)".)