- Manfred Wallner, MD
Manfred Wallner, MD
- Department of Internal Medicine IV
- Section of Nephrology
- Klinikum Wels-Grieskirchen - Wels, Austria
- Reinhard Kramar, MD
Reinhard Kramar, MD
- Former Head of Department of Nephrology
- Klinikum Wels-Grieskirchen- Wels, Austria
- Section Editors
- F Bruder Stapleton, MD
F Bruder Stapleton, MD
- Editor-in-Chief — Pediatrics
- Section Editor — Pediatric Nephrology
- Professor and Chair, Department of Pediatrics
- University of Washington School of Medicine
- Laurence S Baskin, MD, FAAP
Laurence S Baskin, MD, FAAP
- Section Editor — Pediatric Urology
- Frank Hinman, Jr, MD, Distinguished Professorship in Pediatric Urology
- Chief Pediatric Urology
- Professor of Urology and Pediatrics
- UCSF Benioff Children's Hospital
The prune-belly (Eagle-Barrett) syndrome (PBS) is a congenital disorder defined by a characteristic clinical triad (picture 1):
●Abdominal muscle deficiency
●Severe urinary tract abnormalities
●Bilateral cryptorchidism in males
The term "prune-belly" reflects the characteristic wrinkled appearance of the abdominal wall in the newborn due to the complete or partially complete absence of abdominal wall muscles. In adolescent and adult life, the abdomen often assumes a smooth "pot belly" configuration. Contrary to this definition, PBS is in fact a multisystem disease, with patients displaying concomitant cardiopulmonary, gastrointestinal, and musculoskeletal anomalies in varying degree.
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- Fleming SD, Varughese E, Hua VK, et al. Normal live births after intracytoplasmic sperm injection in a man with the rare condition of Eagle-Barrett syndrome (prune-belly syndrome). Fertil Steril 2013; 100:1532.
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- Mesenchymal developmental defect
- Genitourinary tract
- Abdominal wall and gastrointestinal tract
- CLINICAL MANIFESTATIONS
- Other findings
- Antenatal management
- Postnatal management
- - End-stage renal disease
- - Other genitourinary interventions
- - Abdominal wall reconstruction
- - Spinal procedures
- SUMMARY AND RECOMMENDATIONS