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Prothrombin complex concentrates (PCCs) — 4-factor PCC, 3-factor PCC, and activated PCC products: Drug formulations

Author
Jonathan M Zand, PharmD BCPS
Section Editor
Lawrence LK Leung, MD
Deputy Editor
Jennifer S Tirnauer, MD

UNACTIVATED PROTHROMBIN COMPLEX CONCENTRATE: LEXICOMP DRUG INFORMATION MONOGRAPHS

Unactivated prothrombin complex concentrates (also known as factor IX complex) contain the vitamin K-dependent coagulation factors (factors II, VII [in variable amounts], IX, and X) in the unactivated form. Products that contain factor VII are called 4-factor PCC, while those that contain relatively little factor VII are called 3-factor PCC.

4-factor PCC (Beriplex P/N, Octaplex, Kcentra)

Prothrombin complex concentrate, 4-factor, unactivated, from human plasma: Drug information

Prothrombin complex concentrate, 4-factor, unactivated, from human plasma: Patient drug information

3-factor PCC (Bebulin, Profilnine)

Prothrombin complex concentrate, 3-factor, unactivated, from human plasma: Drug information

Prothrombin complex concentrate, 3-factor, unactivated, from human plasma: Pediatric drug information

  

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Literature review current through: Nov 2016. | This topic last updated: Tue Jul 19 00:00:00 GMT+00:00 2016.
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