Prothrombin complex concentrates (PCCs) — 4-factor PCC, 3-factor PCC, and activated PCC products: Drug formulations
- Jonathan M Zand, PharmD BCPS
Jonathan M Zand, PharmD BCPS
- Senior Associate Editor – Drug Information
UNACTIVATED PROTHROMBIN COMPLEX CONCENTRATE: LEXICOMP DRUG INFORMATION MONOGRAPHS
Unactivated prothrombin complex concentrates (also known as factor IX complex) contain the vitamin K-dependent coagulation factors (factors II, VII [in variable amounts], IX, and X) in the unactivated form. Products that contain factor VII are called 4-factor PCC, while those that contain relatively little factor VII are called 3-factor PCC.
4-factor PCC (Beriplex P/N, Octaplex, Kcentra)
3-factor PCC (Bebulin, Profilnine)