Medline ® Abstract for Reference 149
of 'Principles of cancer immunotherapy'
Melanoma vaccines: mixed past, promising future.
Ozao-Choy J, Lee DJ, Faries MB
Surg Clin North Am. 2014 Oct;94(5):1017-30, viii. Epub 2014 Aug 7.
Cancer vaccines were one of the earliest forms of immunotherapy to be investigated. Past attempts to vaccinate against cancer, including melanoma, have mixed results, showing the complexity of what was believed to be a simple concept. However, several recent successes and the combination of improved knowledge of tumor immunology and the advent of new immunomodulators make vaccination a promising strategy for the future.
John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.