Medline ® Abstract for Reference 14
of 'Primary spontaneous pneumothorax in adults'
Familial pneumothoraces and bullae.
The cases of three sisters who presented with spontaneous pneumothoraces are described. In two of the patients large bullae were clearly demonstrable. No recognisable associations of bullae or pneumothorax were present and there was no evidence of generalised emphysema. The cases suggest a familial predisposition to the development of bullae in otherwise apparently healthy lungs.