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Prevention of stroke (initial or recurrent) in sickle cell disease

Author
Alex George, MD, PhD
Section Editor
Donald H Mahoney, Jr, MD
Deputy Editors
Jennifer S Tirnauer, MD
John F Dashe, MD, PhD

INTRODUCTION

Stroke is a common and potentially devastating manifestation of sickle cell disease (SCD) that can affect children and adults. Stroke prevention requires intensive risk assessment and closely monitored interventions for those with increased risk. For many patients, risk reduction involves indefinite chronic transfusion therapy.  

The approach to the prevention of a first or recurrent ischemic stroke (primary and secondary stroke prevention) in individuals with SCD is presented here.

Related aspects of SCD management are discussed in detail separately:

Treatment of acute stroke – (See "Acute stroke in sickle cell disease".)

Blood transfusion – (See "Red blood cell transfusion in sickle cell disease".)

                              

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Literature review current through: Nov 2016. | This topic last updated: Tue Jul 26 00:00:00 GMT+00:00 2016.
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