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Prevention of Candida infection in neonates

Mohan Pammi, MD, PhD
Section Editor
Leonard E Weisman, MD
Deputy Editor
Carrie Armsby, MD, MPH


Candida is a major cause of neonatal infection in preterm infants, especially in extremely low and very low birth weight infants [1-4]. Successful management of neonatal candidiasis requires effective treatment of Candida infection with appropriate antifungal therapy and supportive care, and preventive measures to reduce the risk of systemic Candida infections.

The prevention of Candida infections in neonates will be reviewed here. The clinical manifestations, diagnosis, etiology, risk factors and treatment of neonatal candidal infections are discussed separately. (See "Clinical manifestations and diagnosis of Candida infection in neonates" and "Epidemiology and risk factors for Candida infection in neonates" and "Treatment of Candida infection in neonates".)


Because of the poor clinical outcome of neonates with candidemia, there have been significant efforts to develop preventive measures to reduce the risk of systemic candidal infections. These efforts have focused on the very low and extremely low birth weight infants (birth weight less than 1500 and 1000 g, respectively) who are at the highest risk for invasive candidal infections. (See "Epidemiology and risk factors for Candida infection in neonates", section on 'Epidemiology' and "Epidemiology and risk factors for Candida infection in neonates", section on 'Risk factors for invasive candidiasis'.)

Preventive management includes:

General measures to reduce Candida infection


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Literature review current through: Sep 2016. | This topic last updated: Apr 19, 2016.
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