Medline ® Abstract for Reference 83
of 'Prevention and management of side effects in patients receiving opioids for chronic pain'
Clonazepam treatment of myoclonic contractions associated with high-dose opioids: case report.
Eisele JH Jr, Grigsby EJ, Dea G
A 30-year-old man with chronic abdominal pain was treated with high doses of hydromorphone intravenously and developed severe and frequent myoclonic contractions. Several medications including lorazepam failed to control the contractions; however, clonazepam in normal doses reduced the myoclonus dramatically.
Department of Anesthesiology Pain Service, University of California at Davis, Sacramento.