Prevention and management of growth failure in children with chronic kidney disease
- Burkhard Tönshoff, MD, PhD
Burkhard Tönshoff, MD, PhD
- Professor of Pediatrics and Pediatric Nephrology
- University Children's Hospital, Heidelberg, Germany
Growth retardation is a major complication of children with chronic kidney disease (CKD). Poor growth is a marker of disease severity and is associated with significant morbidity and mortality [1,2].
The prevention and management of growth impairment in children with CKD and after renal transplantation will be reviewed here. The impact, risk factors, and underlying pathogenesis of growth impairment in children with CKD are discussed separately. (See "Pathogenesis, evaluation and diagnosis of growth impairment in children with chronic kidney disease".)
●G1 – Normal GFR (≥90 mL/min per 1.73 m2)
●G2 – GFR between 60 and 89 mL/min per 1.73 m2
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- Chronic kidney disease
- Growth measurement
- SUPPORTIVE MEASURES
- Other supportive measures
- RENAL REPLACEMENT THERAPY
- Continuous peritoneal dialysis
- Corticosteroid therapy
- - Alternate-day corticosteroid
- - Corticosteroid withdrawal or avoidance
- RECOMBINANT HUMAN GROWTH HORMONE THERAPY
- SOCIETY GUIDELINE LINKS
- SUMMARY AND RECOMMENDATIONS