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Prevention and management of growth failure in children with chronic kidney disease

Burkhard Tönshoff, MD, PhD
Section Editor
Patrick Niaudet, MD
Deputy Editor
Melanie S Kim, MD


Growth retardation is a major complication of children with chronic kidney disease (CKD). Poor growth is a marker of disease severity and is associated with significant morbidity and mortality [1,2].

The prevention and management of growth impairment in children with CKD and after renal transplantation will be reviewed here. The impact, risk factors, and underlying pathogenesis of growth impairment in children with CKD are discussed separately. (See "Pathogenesis, evaluation and diagnosis of growth impairment in children with chronic kidney disease".)


Chronic kidney disease — Classification schema for CKD in children is based upon the level of kidney function (defined by glomerular filtration rate [GFR]) as follows (table 1) [3]:

G1 – Normal GFR (≥90 mL/min per 1.73 m2)

G2 – GFR between 60 and 89 mL/min per 1.73 m2


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Literature review current through: Sep 2016. | This topic last updated: Feb 19, 2016.
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