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Prescribing and assessing adequate peritoneal dialysis

John M Burkart, MD
Section Editor
Thomas A Golper, MD
Deputy Editor
Alice M Sheridan, MD


Peritoneal dialysis patient outcomes are affected by the amount of peritoneal dialysis performed and by the amount of residual renal function present. This topic reviews the optimal peritoneal dialysis dose and the determination and preservation of residual renal function.

The assessment of decreased solute clearance and ultrafiltration is discussed elsewhere. (See "Problems with solute clearance and ultrafiltration in continuous peritoneal dialysis" and "Peritoneal equilibration test".)


The optimal amount of peritoneal dialysis that should be performed is not known. Observational studies and at least two prospective, randomized clinical trials have evaluated clinical outcomes in patients who were prescribed the "standard" dose of dialysis compared with those with a "higher" dose of dialysis [1,2]. Based on these data, the following parameters are generally used to guide treatment:

Small solute clearance (using Kt/V as the surrogate)

Residual renal function

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Literature review current through: Oct 2017. | This topic last updated: Oct 01, 2017.
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