Posttreatment follow-up for men with testicular germ cell tumors
- William K Oh, MD
William K Oh, MD
- Section Editor — Testicular Cancer
- Professor of Medicine
- Mount Sinai School of Medicine
- Chief, Division of Hematology Oncology
- Tisch Cancer Institute
- Jerome P Richie, MD, FACS
Jerome P Richie, MD, FACS
- Section Editor — Cancer of the Urethra, Penis, and Ureter; Urologic Surgery; Prostate Cancer
- Elliott Carr Cutler Professor of Surgery
- Harvard Medical School
Testicular germ cell tumors (GCTs) have become one of the most curable solid neoplasms, due to improved staging and surgical techniques, the use of platinum-based combination chemotherapy, and the availability of serum tumor markers (beta subunit of human chorionic gonadotropin [beta-hCG], alpha fetoprotein [AFP], and lactate dehydrogenase [LDH]) to monitor for the response to treatment and the presence of occult disease. For men with testicular GCTs, the five-year survival rate is over 95 percent. (See "Overview of the treatment of testicular germ cell tumors" and "Serum tumor markers in testicular germ cell tumors".)
The follow-up and surveillance for recurrence in men who have completed their initial definitive treatment for testicular cancer will be reviewed here. The use of serum tumor markers during the initial treatment of testicular germ cell tumors is discussed separately.
At the conclusion of treatment, surveillance is appropriate for:
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- ONCOLOGIC FOLLOW-UP
- Duration of follow-up after treatment
- Monitoring approaches
- - History and physical examination
- - Serum tumor markers
- - Radiographic studies
- Guidelines for follow-up
- - NSGCT
- - Seminoma
- Detection of recurrent disease
- - Interpreting serum tumor markers
- - Pulmonary nodules
- - Growing teratoma syndrome
- - False-positive elevation of serum beta-hCG
- TREATMENT-RELATED COMPLICATIONS