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Medline ® Abstract for Reference 103

of 'Postpartum hemorrhage: Medical and minimally invasive management'

103
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Serious primary post-partum hemorrhage, arterial embolization and future fertility: a retrospective study of 46 cases.
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Chauleur C, Fanget C, Tourne G, Levy R, Larchez C, Seffert P
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Hum Reprod. 2008;23(7):1553.
 
BACKGROUND: The guidelines advise arterial embolization in case of post-partum hemorrhage. We evaluated its feasibility and the subsequent fertility.
METHODS: A retrospective study has been conducted in our center for the past 10 years (1996-2005). Fifty-two patients experiencing a primary post-partum hemorrhage who were resistant to medical treatment underwent uterine artery embolization and/or hysterectomy. In case of arterial embolization, a follow-up of all the patients was realized, focusing on the preservation of fertility.
RESULTS: Six (11.5%) patients underwent hysterectomy straightaway and 46 (88.5%) arterial embolization in the first instance including 35 arterial embolizations after Cesarean section. Embolization was successful among 41 patients (89.1%) and hysterectomy was performed on the 5 (10.9%) others. Overall, 11/24 398 women suffered from a definitive loss of fertility after post-partum hemorrhage. Fertility was studied at least 1 year after the delivery. All patients had a return of normal menses. Sixteen of 41 women (39%) wanted anotherchild and 100% succeeded. Nineteen pregnancies, including two twin pregnancy and one early spontaneous abortion were observed.
CONCLUSIONS: Embolization is a safe and effective non-surgical method to resolve post-partum hemorrhage and should be regarded as gold standard in a hemodynamically stable patient. Furthermore, subsequent fertility is not impaired by the procedure.
AD
Department of Gynecology-Obstetrics, University Hospital NORD, F-42055 Saint-Etienne Cedex 2, France. celine.chauleur@chu-st-etienne.fr
PMID