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Postpartum blues and unipolar depression: Prevention and treatment

Peter P Roy-Byrne, MD
Section Editors
Charles J Lockwood, MD, MHCM
Murray B Stein, MD, MPH
Deputy Editor
David Solomon, MD


Although postpartum women are expected to be happy, many are depressed [1-3]. Patients may manifest postpartum blues consisting of mild depressive symptoms that are generally self-limited, or more severe syndromes of minor or major depression.

This topic reviews the management of postpartum blues and the prevention and treatment of postpartum unipolar depression. Other topics discuss the clinical features, assessment, and diagnosis of postpartum blues and unipolar depression; safety of infant exposure to psychotropic drugs through lactation; and diagnosis and treatment of antepartum unipolar depression, postpartum bipolar mood episodes, postpartum psychosis, and postpartum obsessive compulsive disorder (OCD).

(See "Postpartum blues and unipolar depression: Epidemiology, clinical features, assessment, and diagnosis".)

(See "Safety of infant exposure to antidepressants and benzodiazepines through breastfeeding".)

(See "Breastfeeding infants: Safety of exposure to antipsychotics, lithium, stimulants, and medications for substance use disorders".)


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Literature review current through: Sep 2016. | This topic last updated: Jun 8, 2015.
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