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Post-intensive care syndrome (PICS)

Authors
Mark E Mikkelsen, MD, MSCE
Giora Netzer, MD, MSCE
Theodore Iwashyna, MD, PhD
Section Editor
Scott Manaker, MD, PhD
Deputy Editor
Geraldine Finlay, MD

INTRODUCTION

Advances in critical care medicine have resulted in a growing population of survivors of critical illness. Many survivors experience impairment in cognition, mental health, and physical function, known as post-intensive care syndrome (PICS). The mental health of family members may also be adversely affected, which is termed PICS-Family (PICS-F).  

In this topic, we review the definition, epidemiology, clinical manifestations, evaluation, treatment, and outcome of PICS and PICS-F. The management and prognosis of patients following a cardiac arrest and of patients requiring prolonged mechanical ventilation are discussed separately. (See "Prognosis and outcomes following sudden cardiac arrest in adults" and "Management and prognosis of patients requiring prolonged mechanical ventilation".)

DEFINITION

Although there is no official definition for post-intensive care syndrome (PICS), most clinicians agree that PICS constitutes new or worsening function in one or more of the following domains after critical illness (figure 1) [1]:

Cognitive function

Psychiatric function

                           

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Literature review current through: Nov 2016. | This topic last updated: Fri Oct 14 00:00:00 GMT 2016.
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