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Physical activity in patients with chronic kidney disease (including end-stage renal disease and renal transplantation)

Brent W Miller, MD
Section Editor
Daniel C Brennan, MD, FACP
Deputy Editor
Alice M Sheridan, MD


Exercise rehabilitation has been extensively utilized for patients with severe cardiac, pulmonary, and neurologic diseases. Patients with chronic kidney disease (CKD), as well as those with a functional renal allograft, also have physiologic abnormalities that require physical rehabilitation for optimal health [1]. This topic will discuss the underlying causes and treatment of deconditioning in patients with CKD and renal transplant recipients. (See "The benefits and risks of exercise".)


Causes of deconditioning among patients with CKD and renal transplant recipients may include:

Comorbid conditions, including diabetes, cardiac disease, and peripheral vascular disease

Recurrent hospitalization episodes

Uremic myopathy and/or neuropathy (see "Uremic mononeuropathy" and "Uremic polyneuropathy")

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Literature review current through: Oct 2017. | This topic last updated: Jun 15, 2017.
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