Medline ® Abstract for Reference 36
of 'Pharmacologic management of pain during labor and delivery'
36
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The effect of drugs on fetal heart rate variability.
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Petrie RH, Yeh SY, Murata Y, Paul RH, Hon EH, Barron BA, Johnson RJ
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Am J Obstet Gynecol. 1978;130(3):294.
Baseline FHR variability has been quantitated into the mathematical indices of differential index (short-term variability) and interval index (long-term variability). Normal values have been determined. The effect that drugs used during labor have on FHR baseline variability has been evaluated. A clinically meaningful change in variability has been observed following low-dose administration of Demerol, morphine, Nisentil, Phenergan, and Vistaril. A statistically significant increase in variability has been observed following administration of magnesium sulfate.
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PMID