Medline ® Abstract for Reference 15
of 'Peutz-Jeghers syndrome: Screening and management'
Bilateral large-cell calcifying Sertoli cell tumor of the testes with Peutz-Jeghers syndrome: a case report.
Dreyer L, Jacyk WK, du Plessis DJ
Pediatr Dermatol. 1994;11(4):335.
A 13-year-old boy with Peutz-Jeghers syndrome (PJs), gynecomastia, and bilateral multifocal testicular tumors is described. Histology of the testicular tissue disclosed large-cell calcifying Sertoli cell tumors. Females with PJs are known to be at increased risk of developing gonadal tumors. This case and a review of other reported cases suggest that males with PJs are also at risk for developing gonadal tumors.
Department of Anatomical Pathology, University of Pretoria, Republic of South Africa.