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Medline ® Abstract for Reference 62

of 'Pathology of breast cancer'

A review of adenoid cystic carcinoma of the breast with emphasis on its molecular and genetic characteristics.
Vranic S, Bender R, Palazzo J, Gatalica Z
Hum Pathol. 2013 Mar;44(3):301-9. Epub 2012 Apr 18.
Breast carcinomas that do not express estrogen receptorα, progesterone receptor, or human epidermal growth factor receptor 2 are frequently grouped together as "triple negative" and considered an aggressive type of breast malignancy; however, this group is not homogeneous. Adenoid cystic carcinoma of the breast is a rare type of breast cancer with such triple-negative features and, generally, a more favorable clinical course. This comprehensive review describes diagnostic, molecular, and clinical features of adenoid cystic carcinoma and compares them with those of triple-negative breast carcinomas of no special type.