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PANDAS: Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci

Author
Michael E Pichichero, MD
Section Editors
Sheldon L Kaplan, MD
Douglas R Nordli, Jr, MD
Thomas JA Lehman, MD
Deputy Editor
Mary M Torchia, MD

INTRODUCTION

Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci (PANDAS) is a term used to describe a subset of children whose symptoms of obsessive compulsive disorder (OCD) or tic disorders are exacerbated by group A streptococcal (GAS) infection [1]. The hypothesized association between PANDAS and GAS is controversial, as is the limitation of the diagnosis exclusively within the pediatric age group. (See 'Areas of controversy' below.)

An overview of PANDAS will be presented below. The diagnosis, complications, and treatment of GAS infection; OCD; and tic disorders in children are discussed separately:

(See "Group A streptococcal tonsillopharyngitis in children and adolescents: Clinical features and diagnosis".)

(See "Complications of streptococcal tonsillopharyngitis".)

(See "Treatment and prevention of streptococcal tonsillopharyngitis".)

                             

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Literature review current through: Nov 2016. | This topic last updated: Mon Oct 24 00:00:00 GMT 2016.
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